By continuing you agree to the use of cookies. The terpenes of leaves, pollen, and nectar of thyme (Thymus vulgaris) inhibit growth of bee disease-associated microbes. NIH This study provides a potential approach for the development and utilization of natural essential oils and bioactive compunds as novel food additives in the food processing. Pseudomonas aeruginosa was inactivated after thymol and Thymus vulgaris L. essential oil exposure. Medicinal Plants of the Family Lamiaceae in Pain Therapy: A Review. 2015 Aug;18(8):935-7. doi: 10.1089/jmf.2014.0132. Thymus vulgaris L. essential oil (TEO) and thymol are useful for replacing synthetic bacteriostatic agents due to their broad-spectrum bactericidal properties. This site needs JavaScript to work properly. Furthermore, antibacterial activity was investigated against several strains of two Gram-positive (Brochothrix thermosphacta and Staphylococcus aureus) and four Gram-negative food-borne bacteria (Escherichia coli, Salmonella abony, Pseudomonas aeruginosa and P. fragi). In addition to livening up the flavor of food, the thyme plant (Thymus vulgaris) is also the source of thyme essential oil. Please enable it to take advantage of the complete set of features! Results indicate that thymol is the principal component in TEO, as confirmed by GC-MS analysis. Iran J Pharm Res. Nabavi SM, Marchese A, Izadi M, Curti V, Daglia M, Nabavi SF. Pseudomonas aeruginosa is a notoriously difficult pathogen to control with antibiotics and disinfectants. Oil of thyme is derived from thyme, also known as Thymus vulgaris. Sharifi-Rad J, Miri A, Hoseini-Alfatemi SM, Sharifi-Rad M, Setzer WN, Hadjiakhoondi A. Satyal P, Murray BL, McFeeters RL, Setzer WN. Abedi SM, Yarmand F, Motallebnejad M, Seyedmajidi M, Moslemi D, Bijani A, Hosseinimehr SJ. Pain Res Manag. Chemical composition and biological activity of Pulicaria vulgaris essential oil from Iran. eCollection 2018. Thymus vulgaris L. essential oil (TEO) and thymol are useful for replacing synthetic bacteriostatic agents due to their broad-spectrum bactericidal properties. Get the latest public health information from CDC: https://www.coronavirus.gov. P. aeruginosa cell membrane integrity is destroyed as evidenced by an increase in permeability of the inner and outer membranes and the leakage of intracellular biological macromolecules (DNA). The essential oil composition of Thymus vulgaris L. and Rosmarinus officinalis L. endemic to France were determined by GC and GC-MS. Oils were assessed for their cytotoxic, antioxidant and antimicrobial activity. 2018 Jan 16;23(1):185. doi: 10.3390/molecules23010185. The essential oils of four chemotypes of Thymus vulgaris L. (Lamiaceae) were analyzed for their composition and antibacterial activity to assess their different properties. 2016 Oct 27;5(4):70. doi: 10.3390/foods5040070. Food Chem. Plants belonging to the genus Thymus as antibacterial agents: from farm to pharmacy. Thymol and Thymus vulgaris L. essential oil disrupted cell membrane. Clipboard, Search History, and several other advanced features are temporarily unavailable. Our study further confirms that the accumulation of intracellular ROS caused by TEO and thymol can result in oxidative stress-mediated DNA damage. Synergistic Antifungal, Allelopatic and Anti-Proliferative Potential of Salvia officinalis L., and Thymus vulgaris L. Essential Oils. Essential Oil Characterization of Thymus vulgaris from Various Geographical Locations. Epub 2016 Apr 26. Foods. This study focuses on understanding the inhibitory effects of TEO and its major component against P. aeruginosa, and exploring the antibacterial mechanism from the perspectives of cell membrane destruction, DNA intercalation and biofilm prevention. Moreover, TEO and thymol affect the biofilm formation and limit the bacterial swimming and swarming motilities. Miladinović DL, Ilić BS, Kocić BD, Ćirić VM, Nikolić DM. Radioprotective Effect of Thymol Against Salivary Glands Dysfunction Induced by Ionizing Radiation in Rats. Antibacterial Investigation of Thyme Essential Oil and Its Main Constituents in Combination with Tetracycline.  |  The results obtained indicate that, despite their different properties, the essential oils of selected T. vulgaris chemotypes are potent antimicrobials to be employed as useful additives in food products as well as for therapeutic applications. Marchese A, Orhan IE, Daglia M, Barbieri R, Di Lorenzo A, Nabavi SF, Gortzi O, Izadi M, Nabavi SM. 2020 Jun 4;10(6):860. doi: 10.3390/biom10060860. Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. HHS 2015 Apr 15;173:339-47. doi: 10.1016/j.foodchem.2014.10.042. https://doi.org/10.1016/j.lwt.2020.110354. This herb is a member of the mint family, and it’s used for cooking, mouthwashes, potpourri and aromatherapy. Thymol and Thymus vulgaris L. essential oil exhibited antibiofilm formation activity. Thyme oil comes from the perennial herb known as Thymus vulgaris. GC-MS and GC-FID analyses revealed that the essentials oils can be classified into the chemotypes thymol (41.0% thymol), geraniol (26.4% geraniol), linalool (72.5% linalool) and 4-thujanol/terpinen-4-ol (42.2% cis- and 7.3% trans-sabinene hydrate, 6.5 % terpinen-4-ol). NLM Epub 2015 Jan 19. Get the latest research from NIH: https://www.nih.gov/coronavirus. 31 and 37 different compounds were identified representing 99.64% and 99.38% of the thyme and rosemary oils respectively, where oxygenated monoterpenes constituted the main chemical class. Thymol intercalated genomic DNA to impact the normal cellular function. ScienceDirect ® is a registered trademark of Elsevier B.V. ScienceDirect ® is a registered trademark of Elsevier B.V. © 2020 Elsevier Ltd. All rights reserved. Thymol intercalates in the P. aeruginosa genomic DNA to affect the normal function of DNA and even cause bacterial death. Epub 2014 Oct 25. Copyright © 2020 Elsevier B.V. or its licensors or contributors. Uritu CM, Mihai CT, Stanciu GD, Dodi G, Alexa-Stratulat T, Luca A, Leon-Constantin MM, Stefanescu R, Bild V, Melnic S, Tamba BI. Micucci M, Protti M, Aldini R, Frosini M, Corazza I, Marzetti C, Mattioli LB, Tocci G, Chiarini A, Mercolini L, Budriesi R. Biomolecules. TEO and thymol potently combat the planktonic P. aeruginosa and directly change the cell structure. 2016 Nov 1;210:402-14. doi: 10.1016/j.foodchem.2016.04.111. 2016 Fall;15(4):861-866. GC-MS and GC-FID analyses revealed that the essentials oils can be classified into the chemotypes thymol (41.0% thymol), geraniol (26.4% geraniol), linalool (72.5% linalool) and 4-thujanol/terpinen-4-ol (42.2% cis- and 7.3% trans … Alexa E, Sumalan RM, Danciu C, Obistioiu D, Negrea M, Poiana MA, Rus C, Radulov I, Pop G, Dehelean C. Molecules. The essential oil composition of Thymus vulgaris L. and Rosmarinus officinalis L. endemic to France were determined by GC and GC-MS. Oils were assessed for their cytotoxic, antioxidant and … between Thymus vulgaris and Pimpinella anisum essential oils and methanol extracts [24] Thymus vulgaris essential oil: Chemical composition and antimicrobial activity [25] Factors that interact with the antibacterial action of thyme essential oil … … Gram stain, SEM and TEM showed that thyme oil degrades the cell wall and membrane integrity of B. cereus. The antibacterial activities of Thymus vulgaris essential oil and methanol extract could be associated to the presence of phenolic compounds like carvacrol, thymol, -terpinene and p-cymene, which are all reported to have antibacterial … We use cookies to help provide and enhance our service and tailor content and ads. All essential oil samples were demonstrated to be highly effective against Gram-positive strains, whereas the impact on Gram-negative microorganisms was significantly smaller, but still considerable.

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